A new round of scientific and technological revolution and industrial change is constantly breeds, and the manufacturing industry ushered in major changes in technology system, production mode and organization form. Under the influence of intelligent, network, service, green and other new trends, the instrument and instrument enterprises can not be put out. How far is the scientific instrument industry moving towards high-end and quantitative change to qualitative change? Like many industries, there are quite a number of enterprises engaged in instrumentation in China, but in terms of “doing better”, they are long and slow. At the same time, the impact of the new economic form has promoted the fission development of traditional industries. Under this favorable background, the instrumentation industry takes the lead in innovation. For an enterprise, the best product structure must keep pace with the times, to meet the actual needs of the industry, through high-end subdivision into subdivision of the sub industry, to ensure the high profitability of the enterprise. This is also the reason why famous enterprises take root in certain fields, do well, do well and become strong. As far as the shipbuilding industry is concerned, in recent years, the call for improving the localization rate of supporting products has been increasing. However, the development and design level of China’s shipping industry has been relatively limited, many core technologies have not been mastered, some of the high-tech products have not yet realized mass production, and the local brand with great market influence is very rare. There is still a long way to go for shipping high-end market from quantitative change to qualitative change. Petrochemical industry is an important pillar industry of the national economy and plays an important role in promoting the development of national economy. But there are still some problems, such as weak capability of independent innovation, unreasonable industrial layout and so on. The so-called high-end technology is to optimize the product structure and enter the field of high value-added products. The way of high-end business is mainly two kinds of technological breakthrough and merger and acquisition expansion. Jiangsu Tian Rui instrument and other enterprises are able to seize the market share by monopolizing some technology and providing a comprehensive solution. With the development of information technology, more and more smart home appliances are coming into being. The key to continue to pry the market’s consumption potential is to study the consumption habits and needs of the target consumer groups. Put aside the industry’s personality problems, aim at the essential phenomenon of high-end industries in all walks of life. The instrument enterprise should grasp the favorable opportunity, practice the internal work hard, continuously optimize and upgrade the existing products, increase the R & D investment, enhance the R & D capability, strengthen the cooperation of “production, study and research”, improve the core competitiveness, and seize the development opportunities when the market is better. Policy level has also continued to promote the localization rate of instrumentation industry. The state should introduce relevant policies, such as tax reduction, fund support and other policies, encourage enterprises to increase R & D investment, and support the relevant research institutions to purchase domestic instruments and equipment. Mastering the most advanced technology of high-end instrumentation often means mastering the initiative of technological development. We should make up for the lack of high-end instrument industry as soon as possible. Besides focusing on technology development, we should also pay attention to the promotion and use. It is believed that in the development of government departments, scientific researchers and enterprise units, the high-end market layout of the instrument industry in China will be further implemented, and the leap from quantitative change to qualitative change will be realized day by day.